p38 regulates the tumor suppressor PDCD4 via the TSC-mTORC1 pathway

Programmed cell death protein 4 (PDCD4) exerts critical functions as tumor suppressor and in immune cells to regulate inflammatory pro-cesses. The phosphoinositide 3-kinase (PI3K) promotes degradation of PDCD4 via mammalian target of rapamycin complex 1 (mTORC1). How-ever, additional pathways that m...

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Bibliographic Details
Main Authors: Clarissa Braun, Karl Katholnig, Christopher Kaltenecker, Monika Linke, Nyamdelger Sukhbaatar, Markus Hengstschläger, Thomas Weichhart
Format: article
Language:EN
Published: Shared Science Publishers OG 2021
Subjects:
mk2
p38
R
Online Access:https://doaj.org/article/7ec40a35d4504ab8b854afe0d4185ef4
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