p38 regulates the tumor suppressor PDCD4 via the TSC-mTORC1 pathway
Programmed cell death protein 4 (PDCD4) exerts critical functions as tumor suppressor and in immune cells to regulate inflammatory pro-cesses. The phosphoinositide 3-kinase (PI3K) promotes degradation of PDCD4 via mammalian target of rapamycin complex 1 (mTORC1). How-ever, additional pathways that m...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Shared Science Publishers OG
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/7ec40a35d4504ab8b854afe0d4185ef4 |
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