Identification of significant chromatin contacts from HiChIP data by FitHiChIP

HiChIP/PLAC-seq assay is popular for profiling 3D genome interactions among regulatory elements at kilobase resolution. Here the authors describe FitHiChIP an empirical null-based, flexible computational method for statistical significance estimation and loop calling from HiChIP data.

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Auteurs principaux: Sourya Bhattacharyya, Vivek Chandra, Pandurangan Vijayanand, Ferhat Ay
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Q
Accès en ligne:https://doaj.org/article/7ef2ca6ec45b488485c5ff25afb3492e
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