Identification of significant chromatin contacts from HiChIP data by FitHiChIP

HiChIP/PLAC-seq assay is popular for profiling 3D genome interactions among regulatory elements at kilobase resolution. Here the authors describe FitHiChIP an empirical null-based, flexible computational method for statistical significance estimation and loop calling from HiChIP data.

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Autores principales: Sourya Bhattacharyya, Vivek Chandra, Pandurangan Vijayanand, Ferhat Ay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/7ef2ca6ec45b488485c5ff25afb3492e
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spelling oai:doaj.org-article:7ef2ca6ec45b488485c5ff25afb3492e2021-12-02T14:38:43ZIdentification of significant chromatin contacts from HiChIP data by FitHiChIP10.1038/s41467-019-11950-y2041-1723https://doaj.org/article/7ef2ca6ec45b488485c5ff25afb3492e2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11950-yhttps://doaj.org/toc/2041-1723HiChIP/PLAC-seq assay is popular for profiling 3D genome interactions among regulatory elements at kilobase resolution. Here the authors describe FitHiChIP an empirical null-based, flexible computational method for statistical significance estimation and loop calling from HiChIP data.Sourya BhattacharyyaVivek ChandraPandurangan VijayanandFerhat AyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sourya Bhattacharyya
Vivek Chandra
Pandurangan Vijayanand
Ferhat Ay
Identification of significant chromatin contacts from HiChIP data by FitHiChIP
description HiChIP/PLAC-seq assay is popular for profiling 3D genome interactions among regulatory elements at kilobase resolution. Here the authors describe FitHiChIP an empirical null-based, flexible computational method for statistical significance estimation and loop calling from HiChIP data.
format article
author Sourya Bhattacharyya
Vivek Chandra
Pandurangan Vijayanand
Ferhat Ay
author_facet Sourya Bhattacharyya
Vivek Chandra
Pandurangan Vijayanand
Ferhat Ay
author_sort Sourya Bhattacharyya
title Identification of significant chromatin contacts from HiChIP data by FitHiChIP
title_short Identification of significant chromatin contacts from HiChIP data by FitHiChIP
title_full Identification of significant chromatin contacts from HiChIP data by FitHiChIP
title_fullStr Identification of significant chromatin contacts from HiChIP data by FitHiChIP
title_full_unstemmed Identification of significant chromatin contacts from HiChIP data by FitHiChIP
title_sort identification of significant chromatin contacts from hichip data by fithichip
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/7ef2ca6ec45b488485c5ff25afb3492e
work_keys_str_mv AT souryabhattacharyya identificationofsignificantchromatincontactsfromhichipdatabyfithichip
AT vivekchandra identificationofsignificantchromatincontactsfromhichipdatabyfithichip
AT panduranganvijayanand identificationofsignificantchromatincontactsfromhichipdatabyfithichip
AT ferhatay identificationofsignificantchromatincontactsfromhichipdatabyfithichip
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