Identification of significant chromatin contacts from HiChIP data by FitHiChIP

Identification of significant chromatin contacts from HiChIP data by FitHiChIP

HiChIP/PLAC-seq assay is popular for profiling 3D genome interactions among regulatory elements at kilobase resolution. Here the authors describe FitHiChIP an empirical null-based, flexible computational method for statistical significance estimation and loop calling from HiChIP data.

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Detalles Bibliográficos
Autores principales: Sourya Bhattacharyya, Vivek Chandra, Pandurangan Vijayanand, Ferhat Ay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/7ef2ca6ec45b488485c5ff25afb3492e
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