His6, His13, and His14 residues in Aβ 1–40 peptide significantly and specifically affect oligomeric equilibria

Abstract Oligomers of Aβ peptide are implicated as the most probable causative agent in Alzheimer’s disease. However, their structural properties remain elusive due to the dynamic and heterogeneous character of oligomeric species coexisting in solution. Nevertheless, new approaches, mainly based on...

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Autores principales: Kaja Przygońska, Magdalena Pacewicz, Wiktoria Sadowska, Jarosław Poznański, Wojciech Bal, Michał Dadlez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/7f3beb276d5440eb9a6d11c0aedd833e
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