His6, His13, and His14 residues in Aβ 1–40 peptide significantly and specifically affect oligomeric equilibria

Abstract Oligomers of Aβ peptide are implicated as the most probable causative agent in Alzheimer’s disease. However, their structural properties remain elusive due to the dynamic and heterogeneous character of oligomeric species coexisting in solution. Nevertheless, new approaches, mainly based on...

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Auteurs principaux: Kaja Przygońska, Magdalena Pacewicz, Wiktoria Sadowska, Jarosław Poznański, Wojciech Bal, Michał Dadlez
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Q
Accès en ligne:https://doaj.org/article/7f3beb276d5440eb9a6d11c0aedd833e
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