His6, His13, and His14 residues in Aβ 1–40 peptide significantly and specifically affect oligomeric equilibria
Abstract Oligomers of Aβ peptide are implicated as the most probable causative agent in Alzheimer’s disease. However, their structural properties remain elusive due to the dynamic and heterogeneous character of oligomeric species coexisting in solution. Nevertheless, new approaches, mainly based on...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/7f3beb276d5440eb9a6d11c0aedd833e |
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