Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies

The aim of this study was to determine the grain composition and (poly)phenolic profile of pollen from Abrantes (Portugal), as well as its antioxidative and antidiabetic properties, and abilities to protect human erythrocytes against induced hemoglobin oxidation, lipid peroxidation, and hemolysis. T...

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Autores principales:	Ana C. Gonçalves, Radhia Aitfella Lahlou, Gilberto Alves, Cristina Garcia-Viguera, Diego A. Moreno, Luís R. Silva
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	bee pollen phenolic characterization biological potential functional food antioxidant effects Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/7f43a276a86c4d07a49fb8f02b75a27c
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spelling	oai:doaj.org-article:7f43a276a86c4d07a49fb8f02b75a27c2021-11-25T17:35:49ZPotential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies10.3390/foods101128042304-8158https://doaj.org/article/7f43a276a86c4d07a49fb8f02b75a27c2021-11-01T00:00:00Zhttps://www.mdpi.com/2304-8158/10/11/2804https://doaj.org/toc/2304-8158The aim of this study was to determine the grain composition and (poly)phenolic profile of pollen from Abrantes (Portugal), as well as its antioxidative and antidiabetic properties, and abilities to protect human erythrocytes against induced hemoglobin oxidation, lipid peroxidation, and hemolysis. The phytochemical profile of the Abrantes’ bee pollen revealed twenty phenolic compounds, identified by high-performance liquid chromatography with electrospray ionization mass spectrometry coupled with photodiode array detection. Among them, quercetin derivatives were the most abundant. Concerning the biological potential, the pollen extract showed notable capacity for 2,2-diphenyl-1-picrylhydrazyl, nitric oxide, and superoxide radicals, as well as for inhibition of α-glucosidase action, and protection of human erythrocytes against oxidative damage. Non-cytotoxic effects regarding the NHDF normal cell line, human adenocarcinoma Caco-2, and human liver HepG2 cells were observed. The results obtained contributed to further research on modes of action related to oxidative damage and metabolic health problems, to generate deeper knowledge of potential health-promoting effects to develop novel pharmaceutical drugs, nutraceuticals, and dietary supplements.Ana C. GonçalvesRadhia Aitfella LahlouGilberto AlvesCristina Garcia-VigueraDiego A. MorenoLuís R. SilvaMDPI AGarticlebee pollenphenolic characterizationbiological potentialfunctional foodantioxidant effectsChemical technologyTP1-1185ENFoods, Vol 10, Iss 2804, p 2804 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bee pollen phenolic characterization biological potential functional food antioxidant effects Chemical technology TP1-1185
spellingShingle	bee pollen phenolic characterization biological potential functional food antioxidant effects Chemical technology TP1-1185 Ana C. Gonçalves Radhia Aitfella Lahlou Gilberto Alves Cristina Garcia-Viguera Diego A. Moreno Luís R. Silva Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies
description	The aim of this study was to determine the grain composition and (poly)phenolic profile of pollen from Abrantes (Portugal), as well as its antioxidative and antidiabetic properties, and abilities to protect human erythrocytes against induced hemoglobin oxidation, lipid peroxidation, and hemolysis. The phytochemical profile of the Abrantes’ bee pollen revealed twenty phenolic compounds, identified by high-performance liquid chromatography with electrospray ionization mass spectrometry coupled with photodiode array detection. Among them, quercetin derivatives were the most abundant. Concerning the biological potential, the pollen extract showed notable capacity for 2,2-diphenyl-1-picrylhydrazyl, nitric oxide, and superoxide radicals, as well as for inhibition of α-glucosidase action, and protection of human erythrocytes against oxidative damage. Non-cytotoxic effects regarding the NHDF normal cell line, human adenocarcinoma Caco-2, and human liver HepG2 cells were observed. The results obtained contributed to further research on modes of action related to oxidative damage and metabolic health problems, to generate deeper knowledge of potential health-promoting effects to develop novel pharmaceutical drugs, nutraceuticals, and dietary supplements.
format	article
author	Ana C. Gonçalves Radhia Aitfella Lahlou Gilberto Alves Cristina Garcia-Viguera Diego A. Moreno Luís R. Silva
author_facet	Ana C. Gonçalves Radhia Aitfella Lahlou Gilberto Alves Cristina Garcia-Viguera Diego A. Moreno Luís R. Silva
author_sort	Ana C. Gonçalves
title	Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies
title_short	Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies
title_full	Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies
title_fullStr	Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies
title_full_unstemmed	Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies
title_sort	potential activity of abrantes pollen extract: biochemical and cellular model studies
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/7f43a276a86c4d07a49fb8f02b75a27c
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Potential Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies

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