Gene Dosage Effects at the Imprinted Gnas Cluster.

Genomic imprinting results in parent-of-origin-dependent monoallelic gene expression. Early work showed that distal mouse chromosome 2 is imprinted, as maternal and paternal duplications of the region (with corresponding paternal and maternal deficiencies) give rise to different anomalous phenotypes...

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Auteurs principaux: Simon T Ball, Michelle L Kelly, Joan E Robson, Martin D Turner, Jackie Harrison, Lynn Jones, Diane Napper, Colin V Beechey, Tertius Hough, Antonius Plagge, Bruce M Cattanach, Roger D Cox, Jo Peters
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/7f4c01aa4f9a401192e8b77cad145176
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