Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance
The mechanisms that regulate the body’s response to exercise are poorly understood. Here, Rode et al. show that the mechanically activated cation channel Piezo1 is a molecular sensor of physical exercise in the endothelium that triggers endothelial communication to mesenteric vessel muscle cells, le...
Saved in:
Main Authors: | Baptiste Rode, Jian Shi, Naima Endesh, Mark J. Drinkhill, Peter J. Webster, Sabine J. Lotteau, Marc A. Bailey, Nadira Y. Yuldasheva, Melanie J. Ludlow, Richard M. Cubbon, Jing Li, T. Simon Futers, Lara Morley, Hannah J. Gaunt, Katarzyna Marszalek, Hema Viswambharan, Kevin Cuthbertson, Paul D. Baxter, Richard Foster, Piruthivi Sukumar, Andrew Weightman, Sarah C. Calaghan, Stephen B. Wheatcroft, Mark T. Kearney, David J. Beech |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/7f62f67aa840473d94edc1b8db9c890a |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Concerted localization-resets precede YAP-dependent transcription
by: J. Matthew Franklin, et al.
Published: (2020) -
Attentional tuning resets after failures of perceptual awareness.
by: Paul E Dux, et al.
Published: (2013) -
Verification of a resetting protocol for an uncontrolled superconducting qubit
by: Ming Gong, et al.
Published: (2020) -
REVIEW: Coups, globalisation and Fiji’s reset ‘democracy’ paradigm
by: David Robie
Published: (2018) -
Differential associations of ankle and brachial blood pressures with diabetes and cardiovascular diseases: cross-sectional study
by: Hema Viswambharan, et al.
Published: (2021)