Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

ABSTRACT Type III secretion systems (T3SS) translocate effector proteins into target cells in order to disrupt or modulate host cell signaling pathways and establish replicative niches. However, recognition of T3SS activity by cytosolic pattern recognition receptors (PRRs) of the nucleotide-binding...

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Autores principales: Erin E. Zwack, Annelise G. Snyder, Meghan A. Wynosky-Dolfi, Gordon Ruthel, Naomi H. Philip, Melanie M. Marketon, Matthew S. Francis, James B. Bliska, Igor E. Brodsky
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/7f64c014a5aa4c928925802ef24e358f
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