Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

ABSTRACT Type III secretion systems (T3SS) translocate effector proteins into target cells in order to disrupt or modulate host cell signaling pathways and establish replicative niches. However, recognition of T3SS activity by cytosolic pattern recognition receptors (PRRs) of the nucleotide-binding...

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Main Authors: Erin E. Zwack, Annelise G. Snyder, Meghan A. Wynosky-Dolfi, Gordon Ruthel, Naomi H. Philip, Melanie M. Marketon, Matthew S. Francis, James B. Bliska, Igor E. Brodsky
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/7f64c014a5aa4c928925802ef24e358f
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