A novel metagenomic short-chain dehydrogenase/reductase attenuates Pseudomonas aeruginosa biofilm formation and virulence on Caenorhabditis elegans.
In Pseudomonas aeruginosa, the expression of a number of virulence factors, as well as biofilm formation, are controlled by quorum sensing (QS). N-Acylhomoserine lactones (AHLs) are an important class of signaling molecules involved in bacterial QS and in many pathogenic bacteria infection and host...
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Auteurs principaux: | Patrick Bijtenhoorn, Hubert Mayerhofer, Jochen Müller-Dieckmann, Christian Utpatel, Christina Schipper, Claudia Hornung, Matthias Szesny, Stephanie Grond, Andrea Thürmer, Elzbieta Brzuszkiewicz, Rolf Daniel, Katja Dierking, Hinrich Schulenburg, Wolfgang R Streit |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/7f65c5fccdfa4aee913b616311debf7b |
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