GM101 in Combination with Histone Deacetylase Inhibitor Enhances Anti-Tumor Effects in Desmoplastic Microenvironment

Oncolytic adenoviruses (oAds) have been evaluated in numerous clinical trials due to their promising attributes as cancer therapeutics. However, the therapeutic efficacy of oAds was limited due to variable coxsackie and adenovirus receptor (CAR) expression levels and the dense extracellular matrix (...

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Autores principales: Han-Gyu Chang, Yong-Hyeon Choi, JinWoo Hong, Joung-Woo Choi, A-Rum Yoon, Chae-Ok Yun
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/7f74688d253c485e9353a7d625c1d61d
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