Novel p53 therapies for head and neck cancer

Inactivation of the tumor suppressor p53 is the predominant pathogenetic event in head and neck squamous cell carcinoma (HNSCC). The p53 pathway in HNSCC can be compromised through multiple mechanisms including gene mutations, hyperactivation of endogenous negative p53 regulators and by the human pa...

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Autores principales: Mario R. Castellanos, Quintin Pan
Formato: article
Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2016
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Acceso en línea:https://doaj.org/article/7f96e30f0f9547dda9dba2c79df9c3a2
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