Additional sex combs-like 2 is required for polycomb repressive complex 2 binding at select targets.

Polycomb Group (PcG) proteins are epigenetic repressors of gene expression. The Drosophila Additional sex combs (Asx) gene and its mammalian homologs exhibit PcG function in genetic assays; however, the mechanism by which Asx family proteins mediate gene repression is not well understood. ASXL2, one...

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Bibliographic Details
Main Authors: Hsiao-Lei Lai, Q Tian Wang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/7fd4de33c20447fea997fc803c06f152
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