Additional sex combs-like 2 is required for polycomb repressive complex 2 binding at select targets.

Polycomb Group (PcG) proteins are epigenetic repressors of gene expression. The Drosophila Additional sex combs (Asx) gene and its mammalian homologs exhibit PcG function in genetic assays; however, the mechanism by which Asx family proteins mediate gene repression is not well understood. ASXL2, one...

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Autores principales: Hsiao-Lei Lai, Q Tian Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/7fd4de33c20447fea997fc803c06f152
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