Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

Cell cycle progression and lipid metabolism are well-coordinated processes required for proper cell proliferation. In liver diseases that arise from dysregulated lipid metabolism, hepatocyte proliferation is diminished. To study the outcome of CDK1 loss and blocked hepatocyte proliferation on lipid...

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Detalles Bibliográficos
Autores principales: Jin Rong Ow, Matias J Caldez, Gözde Zafer, Juat Chin Foo, Hong Yu Li, Soumita Ghosh, Heike Wollmann, Amaury Cazenave-Gassiot, Chee Bing Ong, Markus R Wenk, Weiping Han, Hyungwon Choi, Philipp Kaldis
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2020
Materias:
liver
lipid metabolism
insulin resistance
hepatic steatosis
cell cycle
CDK1
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/800dcd51bf63414c82eae688da8bc038
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https://doaj.org/article/800dcd51bf63414c82eae688da8bc038

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