Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability
Temporal regulation of microtubule dynamics in mitosis can be achieved by phosphorylation of microtubule plus-end proteins. Here, the authors show that Aurora B and CDK1 phosphorylate EB2, which changes microtubule binding affinity and controls kinetochore microtubule dynamics and genome stability.
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
|
| Subjects: | |
| Online Access: | https://doaj.org/article/802977d060344b0a800fe1f75bcb688a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|