A Mechanism-based QSTR Model for Acute to Chronic Toxicity Extrapolation: A Case Study of Antibiotics on Luminous Bacteria

Abstract The determination of the chronic toxicity is time-consumed and costly, so it’s of great interest to predict the chronic toxicity based on acute data. Current methods include the acute to chronic ratios (ACRs) and the QSTR models, both of which have some usage limitations. In this paper, the...

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Autores principales: Dali Wang, Yue Gu, Min Zheng, Wei Zhang, Zhifen Lin, Ying Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8030a9497df64298ac68d94569644fd1
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