Molecular Mechanisms of mtDNA-Mediated Inflammation

Besides their role in cell metabolism, mitochondria display many other functions. Mitochondrial DNA (mtDNA), the own genome of the organelle, plays an important role in modulating the inflammatory immune response. When released from the mitochondrion to the cytosol, mtDNA is recognized by cGAS, a cG...

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Autores principales: Anna De Gaetano, Kateryna Solodka, Giada Zanini, Valentina Selleri, Anna Vittoria Mattioli, Milena Nasi, Marcello Pinti
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/8051d5b5ce1247289322d7e1526fd3a5
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