Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase

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Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase

Connexin proteins are usually considered as tumor suppressors. Here, the authors show that connexin 26 (Cx26) regulates the self-renewal of breast cancer stem cells via a ternary complex with FAK and NANOG.

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Detalles Bibliográficos
Autores principales:	Praveena S. Thiagarajan, Maksim Sinyuk, Soumya M. Turaga, Erin E. Mulkearns-Hubert, James S. Hale, Vinay Rao, Abeba Demelash, Caner Saygin, Arnab China, Tyler J. Alban, Masahiro Hitomi, Luke A. Torre-Healy, Alvaro G. Alvarado, Awad Jarrar, Andrew Wiechert, Valery Adorno-Cruz, Paul L. Fox, Benjamin C. Calhoun, Jun-Lin Guan, Huiping Liu, Ofer Reizes, Justin D. Lathia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8069efa147334bedbe33b1e19b4d7241
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/8069efa147334bedbe33b1e19b4d7241