Protein conformational transitions explored by a morphing approach based on normal mode analysis in internal coordinates

Large-scale conformational changes are essential for proteins to function properly. Given that these transition events rarely occur, however, it is challenging to comprehend their underlying mechanisms through experimental and theoretical approaches. In this study, we propose a new computational met...

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Auteurs principaux: Byung Ho Lee, Soon Woo Park, Soojin Jo, Moon Ki Kim
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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R
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Accès en ligne:https://doaj.org/article/8071b6acfe5041a5803fac984ae0bd27
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