Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes
Abstract Apples are well known to have various benefits for the human body. Procyanidins are a class of polyphenols found in apples that have demonstrated effects on the circulatory system and skeletal organs. Osteoarthritis (OA) is a locomotive syndrome that is histologically characterized by carti...
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Main Authors: | Isao Masuda, Masato Koike, Shohei Nakashima, Yu Mizutani, Yusuke Ozawa, Kenji Watanabe, Yoko Sawada, Hiroshi Sugiyama, Atsushi Sugimoto, Hidetoshi Nojiri, Koichi Sashihara, Koutaro Yokote, Takahiko Shimizu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/807631a87310403fad916501ca20c8ed |
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