Septal Class A Penicillin-Binding Protein Activity and <scp>ld</scp> -Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter baumannii

The increasing prevalence of antibiotic treatment failure associated with Gram-negative bacterial infections highlights an urgent need to develop new alternative therapeutic strategies. The last-line antimicrobial colistin (polymyxin E) targets the ubiquitous outer membrane lipopolysaccharide (LPS)...

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Bibliographic Details
Main Authors: Katie N. Kang, Misha I. Kazi, Jacob Biboy, Joe Gray, Hannah Bovermann, Jessie Ausman, Cara C. Boutte, Waldemar Vollmer, Joseph M. Boll
Format: article
Language:EN
Published: American Society for Microbiology 2021
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Online Access:https://doaj.org/article/8086c873e9aa4506bcc2a0b60a6154f6
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