Vertically transferred maternal immune cells promote neonatal immunity against early life infections

Maternal immune cells seed into the foetus during mammalian pregnancy, yet the functional role of these cells is unclear. Here the authors show that maternal immune cells in foetal bone marrow stimulate immune development, subsequently reducing the risk or severity of infections in newborns.

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Autores principales: Ina Annelies Stelzer, Christopher Urbschat, Steven Schepanski, Kristin Thiele, Ioanna Triviai, Agnes Wieczorek, Malik Alawi, Denise Ohnezeit, Julian Kottlau, Jiabin Huang, Nicole Fischer, Hans-Willi Mittrücker, Maria Emilia Solano, Boris Fehse, Anke Diemert, Felix R. Stahl, Petra Clara Arck
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8088a7cf93724a69801b759e6eac591e
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