Cellular uptake and antitumor activity of DOX-hyd-PEG-FA nanoparticles.
A PEG-based, folate mediated, active tumor targeting drug delivery system using DOX-hyd-PEG-FA nanoparticles (NPs) were prepared. DOX-hyd-PEG-FA NPs showed a significantly faster DOX release in pH 5.0 medium than in pH 7.4 medium. Compared with DOX-hyd-PEG NPs, DOX-hyd-PEG-FA NPs increased the intra...
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Main Authors: | Wei-liang Ye, Jiang-bo Du, Bang-le Zhang, Ren Na, Yan-feng Song, Qi-bing Mei, Ming-gao Zhao, Si-yuan Zhou |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/80a4eb0980d54e93a5c8da5ddaa2dfef |
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