Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease

Abstract Sickle cell disease (SCD) is one of the most common inherited single gene disorders. Polymerisation of sickle hemoglobin results in erythrocytes that are inflexible and adherent, leading to coagulation, vascular and cellular activation and resultant blood vessel blockage. Previous studies h...

Full description

Saved in:
Bibliographic Details
Main Authors: Rachel A. Smith, Tosti J. Mankelow, Despoina Drizou, Thomas Bullock, Tom Latham, Sara Trompeter, Allison Blair, David J. Anstee
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/80b26d17fb7b4680be25d1d650c7b9a6
Tags: Add Tag
No Tags, Be the first to tag this record!