Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease

Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease

Abstract Sickle cell disease (SCD) is one of the most common inherited single gene disorders. Polymerisation of sickle hemoglobin results in erythrocytes that are inflexible and adherent, leading to coagulation, vascular and cellular activation and resultant blood vessel blockage. Previous studies h...

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Bibliographic Details
Main Authors: Rachel A. Smith, Tosti J. Mankelow, Despoina Drizou, Thomas Bullock, Tom Latham, Sara Trompeter, Allison Blair, David J. Anstee
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/80b26d17fb7b4680be25d1d650c7b9a6
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