Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood

Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood

Abstract The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure induces long-term changes in baseline responses to anxiety-inducing environments, and if so, whether its re-exposure in adulthood would ameliorate this anxiety-like phenotype. An additional goal was to as...

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Bibliographic Details
Main Authors: Francisco J. Flores-Ramirez, Anapaula Themann, Jorge A. Sierra-Fonseca, Israel Garcia-Carachure, Samuel A. Castillo, Minerva Rodriguez, Omar Lira, Joshua Preciado-Piña, Brandon L. Warren, Alfred J. Robison, Sergio D. Iñiguez
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/80c4ded134d041aa88cdd77b4d2e9863
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https://doaj.org/article/80c4ded134d041aa88cdd77b4d2e9863

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