Production and purification of high-titer OrfV for preclinical studies in vaccinology and cancer therapy

Poxviruses have been used extensively as vaccine vectors for human and veterinary medicine and have recently entered the clinical realm as immunotherapies for cancer. We present a comprehensive method for producing high-quality lots of the poxvirus Parapoxvirus ovis (OrfV) for use in preclinical mod...

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Bibliographic Details
Main Authors: Jacob P. van Vloten, Jessica A. Minott, Thomas M. McAusland, Joelle C. Ingrao, Lisa A. Santry, Grant McFadden, James J. Petrik, Byram W. Bridle, Sarah K. Wootton
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/80ee3b897ec94e55bc1c335e48d70703
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