Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine.

Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine.

H5N1 highly pathogenic avian influenza virus (HPAIV) infection has been reported in poultry and humans with expanding clade designations. Therefore, a vaccine that induces immunity against a broad spectrum of H5N1 viruses is preferable for pandemic preparedness. We established a second H5N1 vaccine...

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Main Authors: Misako Nakayama, Shintaro Shichinohe, Yasushi Itoh, Hirohito Ishigaki, Mitsutaka Kitano, Masahiko Arikata, Van Loi Pham, Hideaki Ishida, Naoko Kitagawa, Masatoshi Okamatsu, Yoshihiro Sakoda, Takaya Ichikawa, Hideaki Tsuchiya, Shinichiro Nakamura, Quynh Mai Le, Mutsumi Ito, Yoshihiro Kawaoka, Hiroshi Kida, Kazumasa Ogasawara
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/80f59a51de114539adb638a3ce35ca72
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