CD46 facilitates entry and dissemination of human cytomegalovirus

Human cytomegalovirus (CMV) infects a wide range of host cells. Here, using a high throughput antibody screening platform, the authors identify the cell surface receptor CD46 to be required for CMV infection of epithelial cells and trophoblast-derived cells, the latter critical for congenital CMV in...

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Bibliographic Details
Main Authors: Kathryn R. Stein, Thomas J. Gardner, Rosmel E. Hernandez, Thomas A. Kraus, James A. Duty, Iban Ubarretxena-Belandia, Thomas M. Moran, Domenico Tortorella
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/8106cc357234409b93e70c97eb7e4ea3
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