Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer's disease.

In the current study, we analyzed the effects of the systemic inflammatory response (SIR) and amyloid β (Aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (Cdk) in: (i) PC12 cells overexpressing human beta amyloid precursor protein (βAPP), wild-type (APPwt-PC12), or...

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Autores principales: Grzegorz A Czapski, Magdalena Cieślik, Emilia Białopiotrowicz, Walter J Lukiw, Joanna B Strosznajder
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/8127807ac86f483683a94cab32ca2f3b
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