Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema

Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema

Abstract Acetylcholine (ACh), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. ACh is also involved in a non-neuronal mechanism that modulates the innate immune response. Because inflammation and release of pro-inflammatory cyto...

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Main Authors: Rosana Banzato, Nathalia M. Pinheiro, Clarice R. Olivo, Fernanda R. Santana, Fernanda D. T. Q. S. Lopes, Luciana C. Caperuto, Niels O. Câmara, Milton A. Martins, Iolanda F. L. C. Tibério, Marco Antônio M. Prado, Vânia F. Prado, Carla M. Prado
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/81713456707246e290513a0f1cc1a61e
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https://doaj.org/article/81713456707246e290513a0f1cc1a61e

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