Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

Culex mosquitoes are a global vector for insect-borne diseases, though progress with genetic tools lags behind other mosquito species. Here the authors present a Cas9-based toolkit and methods that could support future gene drive development in these mosquitoes.

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Auteurs principaux: Xuechun Feng, Víctor López Del Amo, Enzo Mameli, Megan Lee, Alena L. Bishop, Norbert Perrimon, Valentino M. Gantz
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/819b1068923347549588f7ff68d80acf
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