Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

Culex mosquitoes are a global vector for insect-borne diseases, though progress with genetic tools lags behind other mosquito species. Here the authors present a Cas9-based toolkit and methods that could support future gene drive development in these mosquitoes.

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Autores principales:	Xuechun Feng, Víctor López Del Amo, Enzo Mameli, Megan Lee, Alena L. Bishop, Norbert Perrimon, Valentino M. Gantz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/819b1068923347549588f7ff68d80acf
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spelling	oai:doaj.org-article:819b1068923347549588f7ff68d80acf2021-12-02T14:58:43ZOptimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes10.1038/s41467-021-23239-02041-1723https://doaj.org/article/819b1068923347549588f7ff68d80acf2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23239-0https://doaj.org/toc/2041-1723Culex mosquitoes are a global vector for insect-borne diseases, though progress with genetic tools lags behind other mosquito species. Here the authors present a Cas9-based toolkit and methods that could support future gene drive development in these mosquitoes.Xuechun FengVíctor López Del AmoEnzo MameliMegan LeeAlena L. BishopNorbert PerrimonValentino M. GantzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xuechun Feng Víctor López Del Amo Enzo Mameli Megan Lee Alena L. Bishop Norbert Perrimon Valentino M. Gantz Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes
description	Culex mosquitoes are a global vector for insect-borne diseases, though progress with genetic tools lags behind other mosquito species. Here the authors present a Cas9-based toolkit and methods that could support future gene drive development in these mosquitoes.
format	article
author	Xuechun Feng Víctor López Del Amo Enzo Mameli Megan Lee Alena L. Bishop Norbert Perrimon Valentino M. Gantz
author_facet	Xuechun Feng Víctor López Del Amo Enzo Mameli Megan Lee Alena L. Bishop Norbert Perrimon Valentino M. Gantz
author_sort	Xuechun Feng
title	Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes
title_short	Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes
title_full	Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes
title_fullStr	Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes
title_full_unstemmed	Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes
title_sort	optimized crispr tools and site-directed transgenesis towards gene drive development in culex quinquefasciatus mosquitoes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/819b1068923347549588f7ff68d80acf
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Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

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