Translation error clusters induced by aminoglycoside antibiotics
Aminoglycoside antibiotics target the ribosome and induce misreading, yet which translation errors induce bacterial cell death is unclear. Here authors use quantitative mass spectrometry and show that bactericidal aminoglycosides induce clusters of errors in full-length proteins in vivo with as many...
Guardado en:
Autores principales: | Ingo Wohlgemuth, Raffaella Garofalo, Ekaterina Samatova, Aybeg Nafiz Günenç, Christof Lenz, Henning Urlaub, Marina V. Rodnina |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/81c575edaca14f1fa23d9fc498664242 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
por: Takayuki Katoh, et al.
Publicado: (2016) -
Thermodynamic Studies of Aminoglycoside Antibiotic-Enzyme Interactions
por: Engin H. Serpersu, et al.
Publicado: (2006) -
ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin
por: Emily Bordeleau, et al.
Publicado: (2021) -
Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2″)-Ia
por: Georgina Cox, et al.
Publicado: (2015) -
Aminoglycoside riboswitch control of the expression of integron associated aminoglycoside resistance adenyltransferases
por: Jun Zhang, et al.
Publicado: (2020)