High content screening identifies monensin as an EMT-selective cytotoxic compound

High content screening identifies monensin as an EMT-selective cytotoxic compound

Abstract Epithelial-to-mesenchymal transition (EMT) is implicated in cancer metastasis and drug resistance. Specifically targeting cancer cells in an EMT-like state may have therapeutic value. In this study, we developed a cell imaging-based high-content screening protocol to identify EMT-selective...

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Autores principales: Marion Vanneste, Qin Huang, Mengshi Li, Devon Moose, Lei Zhao, Mark A. Stamnes, Michael Schultz, Meng Wu, Michael D. Henry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/81d4fbdb3f094595b0c61a1302ce2102
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