Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity

Predicting response to cancer immunotherapy is still a challenge. Here, the authors show that their method of predicting MHC-binding peptides, combined with profiling anti-immunogenic mutations, can better predict the clinical benefit of immunotherapy.

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Auteurs principaux: Kwoneel Kim, Hong Sook Kim, Jeong Yeon Kim, Hyunchul Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Se-Hoon Lee, Jung Kyoon Choi
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/81e385970f0841be95673eae17dd1b1b
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