Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining

Classical non-homologous end-joining (cNHEJ) is the dominant pathway used by human cells to repair DNA double-strand breaks (DSBs) and maintain genome stability. Here the authors show that PARP1-driven chromatin expansion allows the recruitment of ZNF384, which in turn recruits Ku70/Ku80 to facilita...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jenny Kaur Singh, Rebecca Smith, Magdalena B. Rother, Anton J. L. de Groot, Wouter W. Wiegant, Kees Vreeken, Ostiane D’Augustin, Robbert Q. Kim, Haibin Qian, Przemek M. Krawczyk, Román González-Prieto, Alfred C. O. Vertegaal, Meindert Lamers, Sébastien Huet, Haico van Attikum
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/81eb6422ad4941fe875820f223a85fd7
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/81eb6422ad4941fe875820f223a85fd7

Ejemplares similares