Engram-specific transcriptome profiling of contextual memory consolidation

The molecular mechanisms underlying contextual fear memory consolidation by sparse dentate gyrus (DG) neuronal populations remain unclear. Here using unbiased RNA sequencing of DG engram neurons the authors identify persistent transcriptome modifications during memory consolidation, in which CREB-de...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Priyanka Rao-Ruiz, Jonathan J. Couey, Ivo M. Marcelo, Christian G. Bouwkamp, Denise E. Slump, Mariana R. Matos, Rolinka J. van der Loo, Gabriela J. Martins, Mirjam van den Hout, Wilfred F. van IJcken, Rui M. Costa, Michel C. van den Oever, Steven A. Kushner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/81f7aacf83c34678930b62a53ba586ba
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:81f7aacf83c34678930b62a53ba586ba
record_format	dspace
spelling	oai:doaj.org-article:81f7aacf83c34678930b62a53ba586ba2021-12-02T16:58:27ZEngram-specific transcriptome profiling of contextual memory consolidation10.1038/s41467-019-09960-x2041-1723https://doaj.org/article/81f7aacf83c34678930b62a53ba586ba2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09960-xhttps://doaj.org/toc/2041-1723The molecular mechanisms underlying contextual fear memory consolidation by sparse dentate gyrus (DG) neuronal populations remain unclear. Here using unbiased RNA sequencing of DG engram neurons the authors identify persistent transcriptome modifications during memory consolidation, in which CREB-dependent transcription features prominentlyPriyanka Rao-RuizJonathan J. CoueyIvo M. MarceloChristian G. BouwkampDenise E. SlumpMariana R. MatosRolinka J. van der LooGabriela J. MartinsMirjam van den HoutWilfred F. van IJckenRui M. CostaMichel C. van den OeverSteven A. KushnerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Priyanka Rao-Ruiz Jonathan J. Couey Ivo M. Marcelo Christian G. Bouwkamp Denise E. Slump Mariana R. Matos Rolinka J. van der Loo Gabriela J. Martins Mirjam van den Hout Wilfred F. van IJcken Rui M. Costa Michel C. van den Oever Steven A. Kushner Engram-specific transcriptome profiling of contextual memory consolidation
description	The molecular mechanisms underlying contextual fear memory consolidation by sparse dentate gyrus (DG) neuronal populations remain unclear. Here using unbiased RNA sequencing of DG engram neurons the authors identify persistent transcriptome modifications during memory consolidation, in which CREB-dependent transcription features prominently
format	article
author	Priyanka Rao-Ruiz Jonathan J. Couey Ivo M. Marcelo Christian G. Bouwkamp Denise E. Slump Mariana R. Matos Rolinka J. van der Loo Gabriela J. Martins Mirjam van den Hout Wilfred F. van IJcken Rui M. Costa Michel C. van den Oever Steven A. Kushner
author_facet	Priyanka Rao-Ruiz Jonathan J. Couey Ivo M. Marcelo Christian G. Bouwkamp Denise E. Slump Mariana R. Matos Rolinka J. van der Loo Gabriela J. Martins Mirjam van den Hout Wilfred F. van IJcken Rui M. Costa Michel C. van den Oever Steven A. Kushner
author_sort	Priyanka Rao-Ruiz
title	Engram-specific transcriptome profiling of contextual memory consolidation
title_short	Engram-specific transcriptome profiling of contextual memory consolidation
title_full	Engram-specific transcriptome profiling of contextual memory consolidation
title_fullStr	Engram-specific transcriptome profiling of contextual memory consolidation
title_full_unstemmed	Engram-specific transcriptome profiling of contextual memory consolidation
title_sort	engram-specific transcriptome profiling of contextual memory consolidation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/81f7aacf83c34678930b62a53ba586ba
work_keys_str_mv	AT priyankaraoruiz engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT jonathanjcouey engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT ivommarcelo engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT christiangbouwkamp engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT deniseeslump engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT marianarmatos engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT rolinkajvanderloo engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT gabrielajmartins engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT mirjamvandenhout engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT wilfredfvanijcken engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT ruimcosta engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT michelcvandenoever engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation AT stevenakushner engramspecifictranscriptomeprofilingofcontextualmemoryconsolidation
_version_	1718382275662446592

Engram-specific transcriptome profiling of contextual memory consolidation

Ejemplares similares