Selective Chemical Labeling and Sequencing of 5-Hydroxymethylcytosine in DNA at Single-Base Resolution

5-Hydroxymethylcytosine (5hmC), the oxidative product of 5-methylcytosine (5mC) catalyzed by ten-eleven translocation enzymes, plays an important role in many biological processes as an epigenetic mediator. Prior studies have shown that 5hmC can be selectively labeled with chemically modified glucos...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaogang Li, Xinxin Shi, Yin Gong, Wenting Guo, Yuanrui Liu, Chunwei Peng, Yingchun Xu
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://doaj.org/article/82025f80662f4ab5b10c2f6e4ccf937c
Tags: Add Tag
No Tags, Be the first to tag this record!