Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy

Immunotherapy, the reactivation of the immune system to recognize cancer cells, can be accompanied by severe adverse effects. Here, the authors use pharmacovigilance and genomic data to be able to predict which patients might be susceptible to such severe events.

Guardado en:

Detalles Bibliográficos
Autores principales:	Ying Jing, Jin Liu, Youqiong Ye, Lei Pan, Hui Deng, Yushu Wang, Yang Yang, Lixia Diao, Steven H. Lin, Gordon B. Mills, Guanglei Zhuang, Xinying Xue, Leng Han
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/820d18485664421988a48825be7cf0d2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:820d18485664421988a48825be7cf0d2
record_format	dspace
spelling	oai:doaj.org-article:820d18485664421988a48825be7cf0d22021-12-02T17:18:25ZMulti-omics prediction of immune-related adverse events during checkpoint immunotherapy10.1038/s41467-020-18742-92041-1723https://doaj.org/article/820d18485664421988a48825be7cf0d22020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18742-9https://doaj.org/toc/2041-1723Immunotherapy, the reactivation of the immune system to recognize cancer cells, can be accompanied by severe adverse effects. Here, the authors use pharmacovigilance and genomic data to be able to predict which patients might be susceptible to such severe events.Ying JingJin LiuYouqiong YeLei PanHui DengYushu WangYang YangLixia DiaoSteven H. LinGordon B. MillsGuanglei ZhuangXinying XueLeng HanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ying Jing Jin Liu Youqiong Ye Lei Pan Hui Deng Yushu Wang Yang Yang Lixia Diao Steven H. Lin Gordon B. Mills Guanglei Zhuang Xinying Xue Leng Han Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
description	Immunotherapy, the reactivation of the immune system to recognize cancer cells, can be accompanied by severe adverse effects. Here, the authors use pharmacovigilance and genomic data to be able to predict which patients might be susceptible to such severe events.
format	article
author	Ying Jing Jin Liu Youqiong Ye Lei Pan Hui Deng Yushu Wang Yang Yang Lixia Diao Steven H. Lin Gordon B. Mills Guanglei Zhuang Xinying Xue Leng Han
author_facet	Ying Jing Jin Liu Youqiong Ye Lei Pan Hui Deng Yushu Wang Yang Yang Lixia Diao Steven H. Lin Gordon B. Mills Guanglei Zhuang Xinying Xue Leng Han
author_sort	Ying Jing
title	Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
title_short	Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
title_full	Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
title_fullStr	Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
title_full_unstemmed	Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
title_sort	multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/820d18485664421988a48825be7cf0d2
work_keys_str_mv	AT yingjing multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT jinliu multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT youqiongye multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT leipan multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT huideng multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT yushuwang multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT yangyang multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT lixiadiao multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT stevenhlin multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT gordonbmills multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT guangleizhuang multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT xinyingxue multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy AT lenghan multiomicspredictionofimmunerelatedadverseeventsduringcheckpointimmunotherapy
_version_	1718381096405565440

Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy

Ejemplares similares