Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

por Jason J. Zoeller, Roderick T. Bronson, Laura M. Selfors, Gordon B. Mills, Joan S. Brugge
Publicado 2017

Sex-associated molecular differences for cancer immunotherapy

por Youqiong Ye, Ying Jing, Liang Li, Gordon B. Mills, Lixia Diao, Hong Liu, Leng Han
Publicado 2020

Personalized Integrated Network Modeling of the Cancer Proteome Atlas

por Min Jin Ha, Sayantan Banerjee, Rehan Akbani, Han Liang, Gordon B. Mills, Kim-Anh Do, Veerabhadran Baladandayuthapani
Publicado 2018

Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

por Daniel J. McGrail, Lorenzo Federico, Yongsheng Li, Hui Dai, Yiling Lu, Gordon B. Mills, Song Yi, Shiaw-Yih Lin, Nidhi Sahni
Publicado 2018

Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer

por Shreya Mitra, Jeffrey E. Montgomery, Matthew J. Kolar, Gang Li, Kang J. Jeong, Bo Peng, Gregory L. Verdine, Gordon B. Mills, Raymond E. Moellering
Publicado 2017

Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer

por Xinran Li, Victor C. Y. Mak, Yuan Zhou, Chao Wang, Esther S. Y. Wong, Rakesh Sharma, Yiling Lu, Annie N. Y. Cheung, Gordon B. Mills, Lydia W. T. Cheung
Publicado 2019

Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy

por Ying Jing, Jin Liu, Youqiong Ye, Lei Pan, Hui Deng, Yushu Wang, Yang Yang, Lixia Diao, Steven H. Lin, Gordon B. Mills, Guanglei Zhuang, Xinying Xue, Leng Han
Publicado 2020

Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery

por Hui-Ju Hsieh, Wei Zhang, Shu-Hong Lin, Wen-Hao Yang, Jun-Zhong Wang, Jianfeng Shen, Yiran Zhang, Yiling Lu, Hua Wang, Jane Yu, Gordon B. Mills, Guang Peng
Publicado 2018

Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response

por Ioannis K. Zervantonakis, Claudia Iavarone, Hsing-Yu Chen, Laura M. Selfors, Sangeetha Palakurthi, Joyce F. Liu, Ronny Drapkin, Ursula Matulonis, Joel D. Leverson, Deepak Sampath, Gordon B. Mills, Joan S. Brugge
Publicado 2017

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

por Carman K. M. Ip, Patrick K. S. Ng, Kang Jin Jeong, S. H. Shao, Zhenlin Ju, P. G. Leonard, Xu Hua, Christopher P. Vellano, Richard Woessner, Nidhi Sahni, Kenneth L. Scott, Gordon B. Mills
Publicado 2018

Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

por Zhao Zhang, Joo-Hyung Lee, Hang Ruan, Youqiong Ye, Joanna Krakowiak, Qingsong Hu, Yu Xiang, Jing Gong, Bingying Zhou, Li Wang, Chunru Lin, Lixia Diao, Gordon B. Mills, Wenbo Li, Leng Han
Publicado 2019

Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

por Daniel J. McGrail, Curtis Chun-Jen Lin, Jeannine Garnett, Qingxin Liu, Wei Mo, Hui Dai, Yiling Lu, Qinghua Yu, Zhenlin Ju, Jun Yin, Christopher P. Vellano, Bryan Hennessy, Gordon B. Mills, Shiaw-Yih Lin
Publicado 2017

p85β regulates autophagic degradation of AXL to activate oncogenic signaling

por Ling Rao, Victor C. Y. Mak, Yuan Zhou, Dong Zhang, Xinran Li, Chloe C. Y. Fung, Rakesh Sharma, Chao Gu, Yiling Lu, George L. Tipoe, Annie N. Y. Cheung, Gordon B. Mills, Lydia W. T. Cheung
Publicado 2020

Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

por Myoung-Hee Kang, Hyunji Choi, Masanobu Oshima, Jae-Ho Cheong, Seokho Kim, Jung Hoon Lee, Young Soo Park, Hueng-Sik Choi, Mi-Na Kweon, Chan-Gi Pack, Ju-Seog Lee, Gordon B. Mills, Seung-Jae Myung, Yun-Yong Park
Publicado 2018

Author Correction: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

por Myoung-Hee Kang, Hyunji Choi, Masanobu Oshima, Jae-Ho Cheong, Seokho Kim, Jung Hoon Lee, Young Soo Park, Hueng-Sik Choi, Mi-Na Kweon, Chan-Gi Pack, Ju-Seog Lee, Gordon B. Mills, Seung-Jae Myung, Yun-Yong Park
Publicado 2018

Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics

por Allen Li, Jamie M. Keck, Swapnil Parmar, Janice Patterson, Marilyne Labrie, Allison L. Creason, Brett E. Johnson, Molly Downey, George Thomas, Carol Beadling, Laura M. Heiser, Annette Kolodzie, Alexander R. Guimaraes, Christopher L. Corless, Joe W. Gray, Gordon B. Mills, Raymond C. Bergan, Zahi I. Mitri
Publicado 2021

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

por Hyoung Kim, Haineng Xu, Erin George, Dorothy Hallberg, Sushil Kumar, Veena Jagannathan, Sergey Medvedev, Yasuto Kinose, Kyle Devins, Priyanka Verma, Kevin Ly, Yifan Wang, Roger A. Greenberg, Lauren Schwartz, Neil Johnson, Robert B. Scharpf, Gordon B. Mills, Rugang Zhang, Victor E. Velculescu, Eric J. Brown, Fiona Simpkins
Publicado 2020

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

por Caitlin L. Grzeskowiak, Samrat T. Kundu, Xiulei Mo, Andrei A. Ivanov, Oksana Zagorodna, Hengyu Lu, Richard H. Chapple, Yiu Huen Tsang, Daniela Moreno, Maribel Mosqueda, Karina Eterovic, Jared J. Fradette, Sumreen Ahmad, Fengju Chen, Zechen Chong, Ken Chen, Chad J. Creighton, Haian Fu, Gordon B. Mills, Don L. Gibbons, Kenneth L. Scott
Publicado 2018

Transient commensal clonal interactions can drive tumor metastasis

por Suha Naffar-Abu Amara, Hendrik J. Kuiken, Laura M. Selfors, Timothy Butler, Marco L. Leung, Cheuk T. Leung, Elaine P. Kuhn, Teodora Kolarova, Carina Hage, Kripa Ganesh, Richard Panayiotou, Rosemary Foster, Bo R. Rueda, Athena Aktipis, Paul Spellman, Tan A. Ince, Joanne Xiu, Matthew Oberley, Zoran Gatalica, Nicholas Navin, Gordon B. Mills, Rodrick T. Bronson, Joan S. Brugge
Publicado 2020

Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response

por Dimitra Georgopoulou, Maurizio Callari, Oscar M. Rueda, Abigail Shea, Alistair Martin, Agnese Giovannetti, Fatime Qosaj, Ali Dariush, Suet-Feung Chin, Larissa S. Carnevalli, Elena Provenzano, Wendy Greenwood, Giulia Lerda, Elham Esmaeilishirazifard, Martin O’Reilly, Violeta Serra, Dario Bressan, IMAXT Consortium, Gordon B. Mills, H. Raza Ali, Sabina S. Cosulich, Gregory J. Hannon, Alejandra Bruna, Carlos Caldas
Publicado 2021