PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma

by Tianrun Liu, Wenjuan Ma, Haineng Xu, Menggui Huang, Duo Zhang, Zhenqiang He, Lin Zhang, Steven Brem, Donald M. O’Rourke, Yanqing Gong, Yonggao Mou, Zhenfeng Zhang, Yi Fan
Published 2018

Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α

by Qirui Wang, Zhenqiang He, Menggui Huang, Tianrun Liu, Yanling Wang, Haineng Xu, Hao Duan, Peihong Ma, Lin Zhang, Scott S. Zamvil, Juan Hidalgo, Zhenfeng Zhang, Donald M. O’Rourke, Nadia Dahmane, Steven Brem, Yonggao Mou, Yanqing Gong, Yi Fan
Published 2018

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

by Hyoung Kim, Haineng Xu, Erin George, Dorothy Hallberg, Sushil Kumar, Veena Jagannathan, Sergey Medvedev, Yasuto Kinose, Kyle Devins, Priyanka Verma, Kevin Ly, Yifan Wang, Roger A. Greenberg, Lauren Schwartz, Neil Johnson, Robert B. Scharpf, Gordon B. Mills, Rugang Zhang, Victor E. Velculescu, Eric J. Brown, Fiona Simpkins
Published 2020