Enantioselective formal carbene insertion into C–N bond of aminal as a concise track to chiral α-amino-β2,2-amino acids and synthetic applications

Chiral α-amino-β2,2-amino acid is an ubiquitous fragment that presents in natural products, pharmaceuticals, and bioactive molecules. However, the catalytic enantioselective synthesis of α-amino-β2,2-amino acids with structural complexity and diversity remains a significant challenge. Herein, a high...

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Auteurs principaux: Xue Tian, Xinfang Xu, Tongfei Jing, Zhenghui Kang, Wenhao Hu
Format: article
Langue:EN
Publié: KeAi Communications Co. Ltd. 2021
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Accès en ligne:https://doaj.org/article/821f54f41be3412c8d1940f64d794a20
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