Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)

HIV infection refers to socially significant diseases. As a result of the wide coverage of effective antiretroviral therapy for people living with HIV, the rates of AIDS-related mortality have significantly decreased. At the same time, there was a noticeable increase in morbidity and mortality from...

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Autores principales: Andrei D. Kaprin, Evgenii E. Voronin, Vadim V. Rassokhin, Vladimir V. Rozenberg, Anastasyia V. Nekrasova, Natalia A. Falaleeva, Sergei A. Ivanov, Lyudmila Y. Grivtsova
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Publicado: IP Habib O.N. 2021
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Acceso en línea:https://doaj.org/article/82439449d97641aeb0862f89d4061da2
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spelling oai:doaj.org-article:82439449d97641aeb0862f89d4061da22021-11-30T16:55:01ZMalignant neoplasms associated with HIV infection. Problems and solutions (problem outline)1815-14341815-144210.26442/18151434.2021.3.201041https://doaj.org/article/82439449d97641aeb0862f89d4061da22021-11-01T00:00:00Zhttps://modernonco.orscience.ru/1815-1434/article/viewFile/80666/pdfhttps://doaj.org/toc/1815-1434https://doaj.org/toc/1815-1442HIV infection refers to socially significant diseases. As a result of the wide coverage of effective antiretroviral therapy for people living with HIV, the rates of AIDS-related mortality have significantly decreased. At the same time, there was a noticeable increase in morbidity and mortality from other non-AIDS-related diseases, not the last place in this list is occupied by malignant neoplasms. A decrease in the frequency of AIDS-associated tumors and an increase in the proportion of AIDS-unassociated tumors are significant changes in the structure of malignant neoplasms. There is a complex relationship between HIV-induced immune suppression, chronic antigenic stimulation and concomitant oncogenic viral infections, which increases the risk of developing malignant tumors in these patients. People living with HIV have higher rates of cancer mortality associated with both the lack of adequate antitumor therapy, complications of treatment, and the existence of a direct relationship between immunosuppression and tumor progression. This article analyzes the problems that arise in the treatment of oncological HIV-infected patients, and offers specific practical steps to solve complex interdisciplinary problems.Andrei D. KaprinEvgenii E. VoroninVadim V. RassokhinVladimir V. RozenbergAnastasyia V. NekrasovaNatalia A. FalaleevaSergei A. IvanovLyudmila Y. GrivtsovaIP Habib O.N.articleoncologyhiv infectionaids-associated tumorsaids-non-associated tumorsantiretroviral therapypeople living with hiv infectionNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282RUСовременная онкология, Vol 23, Iss 3, Pp 502-507 (2021)
institution DOAJ
collection DOAJ
language RU
topic oncology
hiv infection
aids-associated tumors
aids-non-associated tumors
antiretroviral therapy
people living with hiv infection
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle oncology
hiv infection
aids-associated tumors
aids-non-associated tumors
antiretroviral therapy
people living with hiv infection
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Andrei D. Kaprin
Evgenii E. Voronin
Vadim V. Rassokhin
Vladimir V. Rozenberg
Anastasyia V. Nekrasova
Natalia A. Falaleeva
Sergei A. Ivanov
Lyudmila Y. Grivtsova
Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)
description HIV infection refers to socially significant diseases. As a result of the wide coverage of effective antiretroviral therapy for people living with HIV, the rates of AIDS-related mortality have significantly decreased. At the same time, there was a noticeable increase in morbidity and mortality from other non-AIDS-related diseases, not the last place in this list is occupied by malignant neoplasms. A decrease in the frequency of AIDS-associated tumors and an increase in the proportion of AIDS-unassociated tumors are significant changes in the structure of malignant neoplasms. There is a complex relationship between HIV-induced immune suppression, chronic antigenic stimulation and concomitant oncogenic viral infections, which increases the risk of developing malignant tumors in these patients. People living with HIV have higher rates of cancer mortality associated with both the lack of adequate antitumor therapy, complications of treatment, and the existence of a direct relationship between immunosuppression and tumor progression. This article analyzes the problems that arise in the treatment of oncological HIV-infected patients, and offers specific practical steps to solve complex interdisciplinary problems.
format article
author Andrei D. Kaprin
Evgenii E. Voronin
Vadim V. Rassokhin
Vladimir V. Rozenberg
Anastasyia V. Nekrasova
Natalia A. Falaleeva
Sergei A. Ivanov
Lyudmila Y. Grivtsova
author_facet Andrei D. Kaprin
Evgenii E. Voronin
Vadim V. Rassokhin
Vladimir V. Rozenberg
Anastasyia V. Nekrasova
Natalia A. Falaleeva
Sergei A. Ivanov
Lyudmila Y. Grivtsova
author_sort Andrei D. Kaprin
title Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)
title_short Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)
title_full Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)
title_fullStr Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)
title_full_unstemmed Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline)
title_sort malignant neoplasms associated with hiv infection. problems and solutions (problem outline)
publisher IP Habib O.N.
publishDate 2021
url https://doaj.org/article/82439449d97641aeb0862f89d4061da2
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