Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

ABSTRACT Bacterial superinfections are a primary cause of death during influenza pandemics and epidemics. Type I interferon (IFN) signaling contributes to increased susceptibility of mice to bacterial superinfection around day 7 post-influenza A virus (IAV) infection. Here we demonstrate that the re...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kelly M. Shepardson, Kyle Larson, Rachelle V. Morton, Justin R. Prigge, Edward E. Schmidt, Victor C. Huber, Agnieszka Rynda-Apple
Format: article
Langue:EN
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://doaj.org/article/82538702d9634950a37811b419608ec6
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!