Rho/ROCK Pathway and Noncoding RNAs: Implications in Ischemic Stroke and Spinal Cord Injury

Ischemic strokes (IS) and spinal cord injuries (SCI) are major causes of disability. RhoA is a small GTPase protein that activates a downstream effector, ROCK. The up-regulation of the RhoA/ROCK pathway contributes to neuronal apoptosis, neuroinflammation, blood-brain barrier dysfunction, astroglios...

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Auteurs principaux: Tetsu Kimura, Yuta Horikoshi, Chika Kuriyagawa, Yukitoshi Niiyama
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
Rho
Accès en ligne:https://doaj.org/article/825ffe2bb9ec48eb8412a7d27adc8b16
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