Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals

Genetic elements that control inflammatory gene expression are not fully elucidated. Here the authors conduct a multi-species analysis of chromatin landscape and NF-κB binding in response to the proinflammatory cytokine TNFα, finding that conserved NF-κB bound regions are linked to enhancer activity...

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Auteurs principaux: Azad Alizada, Nadiya Khyzha, Liangxi Wang, Lina Antounians, Xiaoting Chen, Melvin Khor, Minggao Liang, Kumaragurubaran Rathnakumar, Matthew T. Weirauch, Alejandra Medina-Rivera, Jason E. Fish, Michael D. Wilson
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/8269d7eb565b4f2d87f9bcd58c9accef
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