Tum/RacGAP functions as a switch activating the Pav/kinesin-6 motor

Centralspindlin consists of dimeric kinesin-6 and dimeric RacGAP, and is involved in the organization of anaphase midzone microtubules. Here, the authors show that the RacGAP is needed for motor activity at the plus-end of microtubules, but not for the bundling activity associated with kinesin-6.

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Detalles Bibliográficos
Autores principales: Li Tao, Barbara Fasulo, Brandt Warecki, William Sullivan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/82744fb30fab4a969fdb2f06d28fb301
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